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Title: The role of coagulation factors in the regulation of bronchial epithelial repair in vitro
Author: Ewen, Darleen
Awarding Body: University of Portsmouth
Current Institution: University of Portsmouth
Date of Award: 2007
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The bronchial epithelium serves as a protective cellular barrier and the first site of contact for damaging inflammatory and physical stimuli from the environment. Previous in vivo studies in guinea pigs have demonstrated that normal bronchial epithelial repair is both rapid, and dependent on the formation of a provisional fibrin matrix that is exclusively plasma-derived. This study tests the hypothesis that local release of coagulation factors from bronchial epithelial cells and subsequent fibrin formation supports bronchial epithelial repair independently of plasma proteins.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available