Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.459102
Title: Structures of polysaccharides elaborated by cariogenic organisms
Author: Higton, Frederick Raymond
Awarding Body: University of London
Current Institution: Royal Holloway, University of London
Date of Award: 1975
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Abstract:
The structures of the extracellular polysaccharides elaborated by Streptococcus mutans 03-5 and S. mutans OMZ 51 were investigated. These were fractionated into soluble fractions (GS-5B and OMZ 51B polysaccharides) and lesser-soluble fractions (GS-5A and OMZ 51A polysaccharides). GS-5B polysaccharide was essentially an a linked polyglucan in which 17% of the glucose units were linked through positions 1, 3 and 6 and formed branch points. 60% of the molecule comprised a single -linked glucose chain and the minimum average external chain length was 2. The polysaccharide was poly-dispersed M - 49)000 with a structurally similar low molecularweight fraction = 10,000. The following average repeating unit was proposed. GS-5A polysaccharide contained approximately 35% fructose and 40% of glucose. The polyglucan was linked through positions 1,3 and 6 and formed branch points. Approximately 3% of the glucose units were linked, through positions 1 and 3 only. An average repeating unit was proposed.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.459102  DOI: Not available
Keywords: Biochemistry
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