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Title: Differential pulse polarographic study of drug compounds
Author: Fayad, Nabil M. M.
Awarding Body: Loughborough University of Technology
Current Institution: Loughborough University
Date of Award: 1979
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The work discussed in this thesis is in three parts. The initial work carried out was to develop a differential pulse polarographic (DPP) method for the determination of disodium cromoglycate (INTAL) in human urine samples. The method eventually recommended involves an ion-pair extraction of the cromoglycate with tri-n-butylbenzylphosphonium chloride into chloroform. After evaporating the chloroform and dissolving the residue in a buffer solution, down to 0.5 μg INTAL per ml urine can be determined. The method has the distinct advantages of simplicity and speed over the colorimetric method currently in use.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available