Use this URL to cite or link to this record in EThOS: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.437382
Title: Computational modelling and molecular dynamics simulations of ligand-gated ion channels
Author: Amiri, Shiva
Awarding Body: University of Oxford
Current Institution: University of Oxford
Date of Award: 2006
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Abstract:
Torpedo AChR structure was used to make models of other LGICs. Coarse-grain MD allowed the identification of residues in the TM domain interacting with the lipid-bilayer. Born energy profiles through LGIC pores reveal that the EC domain plays a key role in ion selectivity.
Supervisor: Sansom, Mark S. Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID: uk.bl.ethos.437382  DOI: Not available
Keywords: Ion channels ; Models ; Molecular aspects ; Molecular dynamics ; Ligands (Biochemistry) ; Synapses
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