Use this URL to cite or link to this record in EThOS:
Title: The biocompatibility of novel phosphorylcholine based biomaterials
Author: Barraud, Joanne Elizabeth
Awarding Body: University of Brighton
Current Institution: University of Brighton
Date of Award: 2001
Availability of Full Text:
Access through EThOS:
Access through Institution:
Many conventional biomaterials fail to meet the demands required of them with respect to their surface and bulk properties. This problem can be addressed by developing novel biomaterials that have the desired bulk properties and increased biocompatibility. Alternatively the surfaces of biomaterials which have the desired bulk properties can be modified to increase their biocompatibility without compromising these bulk properties. Phosphorylcholine (PC) based coatings mimic the surface of biological membranes and so offer a novel method for modifying bulk materials, or can be incorporated into novel bulk biomaterials. One of the key issues of biocompatibility is the continual stimulation of the inflammatory response by biomaterials characterised in part by complement activation, macrophage adhesion and granulocyte activation.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: B000 Health Professions Materials Biomedical engineering Biochemical engineering