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Title: Factors affecting bone mineralization and matrix turnover in sheep and cattle
Author: Damir, H. Abu
ISNI:       0000 0001 3403 0580
Awarding Body: University of Aberdeen
Current Institution: University of Aberdeen
Date of Award: 1992
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1. A series of experiments were carried out to look at the effects of a change in blood acid-base status on calcium and phosphorus metabolism in growing lambs and in the near term pregnant dairy cow. 2. In the first experiment three groups of lambs about 25 kg live weight were fed a basal diet either on its own or supplemented with 10 g/kg ammonium chloride (acid diet) or 20 g/kg sodium bicarbonate (alkaline diet). At about 45 kg live weight the lambs were killed and their body composition was determined. The composition of their gains was also determined using data obtained from a further group of lambs killed at the start of the experiment. 3. Lambs fed the acid diet showed a fall in blood and urine pH similar to that seen in lambs fed a concentrate diet while those fed the alkaline diet showed increases to levels similar to those seen in lambs fed on forage diets. 4. There were also marked effects on calcium (Ca), phosphorus (P) and Mg retention with the retentions of these minerals being reduced in those fed the acid diet and increased in those fed the alkaline diet. 5. The average rates of retention of Ca and P in lambs fed the alkaline diet were 9.1 and 5.9 g/kg empty body weight gain and are comparable with rates seen in lambs fed forage diets. Values for lambs fed the acid diet were 6.2 and 4.7 g/kg empty body weight and were similar to rates seen previously in lambs fed concentrate diets and points to dietary-induced changes in blood acid-base status as being the major factor contributing to the lower rates of retention seen in lambs fed acid diets. 6. In a further experiment two groups of lambs fed either acid or alkaline diets similar in composition to those used in the previous experiment were allowed to grow from 25 to 35 kg live weight over a period of eight weeks. At the end of this period they were transferred to metabolism cages that allowed the separate collection of urine and faeces.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Zoology Zoology Veterinary medicine