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Title: Routes to chiral N-acyliminium ion precursors for the synthesis of optically active pure ring-fused pyrroloisoquinoline alkaloids
Author: James, Stella L.
Awarding Body: Loughborough University
Current Institution: Loughborough University
Date of Award: 2003
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Pyrrolisoquinoline (B) is found as a major structural motif of the erythrina alkaloid group of natural products. We recognised that a suitably substituted bicyclic lactam (A) could act as a precursor in an intramolecular N-acyliminium mediated cyclisation reaction in a stereoselective approach to the core of the erythrinane target ring system.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Erythrina alkaloid Chemistry, Organic