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Title: The effects of moisture on triboelectrification of selected pharmaceutical excipient powders
Author: Mackin, L. A.
Awarding Body: University of Sunderland
Current Institution: University of Sunderland
Date of Award: 1995
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The literature contains conflicting reports on the effect of moisture on triboelectrification, indeed experiments have shown moisture to increase, decrease or have no effect at all on the charging of solids. The research programme investigated the role of moisture in the triboelectrification of a range of pharmaceutical excipients. Selection of excipients was made on the basis of a) moisture sorption capacity (the starch group) and b) potential use in dry powder inhaler formulations (the sugar and sorbitol group). The following excipients were selected for preliminary investigations:- a-lactose monohydrate, dextrose monohydrate, sorbitol spray dried (SSD), sorbitol powder, sucrose, maize and potato starch and Primojelâ„¢.
Supervisor: Not available Sponsor: Not available
Qualification Name: Thesis (Ph.D.) Qualification Level: Doctoral
EThOS ID:  DOI: Not available
Keywords: Pharmacology & pharmacy & pharmaceutical chemistry Pharmacology